Dementia Science

Memory Circuits Team (Michel van den Oever) and Alzheimer Team (Ronald van Kesteren) join forces to test how hyperactive interneurons affect the formation and reactivation of memory engrams. They receive a 300 k€ grant from Alzheimer Nederland to investigate this.

A new study by PhD student Sara Hijazi (MCN) shows that reducing the activity of interneurons in the hippocampus restores memory and delays Alzheimer’s disease progression in mice. The study is published in Molecular Psychiatry.

A new study by PhD student Martina Rosato (MCN) shows that combined cellular and molecular profiling is able to reveal novel biological insight into the polygenic nature of schizophrenia. The study was published last month in Molecular Psychiatry.

Research team led by Ronald van Kesteren receives 675 k€ to investigate changes in brain activity that can provide new diagnostic markers or treatment targets for early-stage Alzheimer’s disease.